Central serous chorioretinopathy after local application of glucocorticoids for skin disorders.

the silicone material. Clinically significant postoperative opacification of hydrophilic acrylic IOL (model SC60B-OUV; Medical Developmental Research, Inc, Clearwater, Fla) has been reported. This has been reportedly due to the presence of granular deposits within the optic of the lens, which were naturally occurring calcium produced by the patient’s body. In our department we performed 8 cases of routine uneventful phacoemulsification with implantation of the Aquasense IOL (Ophthalmic Innovations, Inc) by 3 different surgeons between October and November 2000. This was a single-piece foldable hydrophilic acrylic IOL (water content, 25%). The patients in 5 of these cases had significant visual deterioration due to total opacification of the IOL more than a year after surgery. The whole lens had diffuse opacification within its substance and was uniformly distributed. All of them had a similar pattern of opacification with minimal variation. No apparent cause for the opacification of the IOL could be found. The company’s managing director in the United Kingdom was contacted (Ophthalmic Innovations, Inc, oral communication, November 2002). He explained that the opacification was due to an interaction between the silicone sleeve, used to hold the IOL in the vial, and the acrylic material of the IOL itself. This apparently imparted a negative charge to the IOL resulting in its opacification. To our knowledge no other case has been reported in the literature where the whole IOL has opacified. The company refused to give out “proprietary” information on the exact number of IOLs that had been implanted, but an educated guess would be over 500. Apparently all these IOLs have been withdrawn and a modified version without the silicone sleeve has been introduced. Apparently no opacification has been reported so far with this new version. We have had no further experience with this IOL.